Practical Bioinformatics 'Protein Structure and Function Analysis'

 

Type:

Practical (10 SWS)

Ects:

12.0

Level:

Master Bioinformatics

Lecturer:

Dr. Andrea Schafferhans, Dr. Edda Kloppmann, Dr. Lothar Richter

Pre-Meeting:

Thursday, 21.2.2013, 12:00,  seminar room 01.09.034

Rotations:

Tuesday 10:00 - 12:00

Place:

Meetings: seminar room 01.09.034; Work: Praktikum room 01.08.021

Language:

English

Preliminary discussion and registration

There will be a preliminary discussion (see above). There, we will give a general overview of the course and recommend reading material. 

 

Content

The practical will be focussed around analysis and prediction of the effects of disease-causing mutations in the human genome. To this end, we will apply sequence analysis methods and structure prediction methods. Participants will learn the theoretical basis of the methods, how to apply them in practice and how to interpret and validate the results. 

All of this can and should be driven by the interest of the participants. We hope to incite our pariticipants' curiosity and would like to support their quest for answers to the questions they decide to address.

The students will build a wiki, where they collect all information relevant to the studied diseases and where they document the methods used and the obtained results.

Criteria to pass

  • 10 min introductory talk
  • 15 min presentation  about a method used for structure and fuction prediction
  • Oral contribution
  • Wiki entries about the tasks performed during the practical
  • Final report: research paper